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Abstracts of the 22

nd

National Congress of Digestive Diseases / Digestive and Liver Disease 48S2 (2016) e67–e231

e127

presence of a large obstructive stone in the duodenal bulb, unable to

be removed endoscopically even after pyloric dilation. To improve

the obstructive symptoms, the patient underwent gastro-jejunal

anastomosis with partial relief of the obstruction. In order to

fragment the stone, we performed another endoscopic procedure. A

laser Holmium YAG 30 W (HLS30W, Olympus GmbH) treatment was

applied for a total of about 200 minutes which resulted in stone’s

fragmentation into small parts removed by extraction basket and

retrieval device.

Results:

The patient was discharged 15 days after with a complete

resolution of the occlusive symptoms. The cholecystectomy was

cancelled.

Conclusions:

Holmium laser lithotripsy is safe and effective in the

treatment of a large impacted gallstone in the duodenum.

V.02.9

AN INDETERMINATE BILIARY STRICTURES ASSESSED USING THE

NEXT GENERATION SPYGLASS DS SYSTEM: A VIDEO CASE

Murino A.*, Pedroni N., Pisanu R., Pinna R., Sanna P., Zaru S., Cugia L.

Ospedale Civile SS Annunziata, Sassari, Italy

Background and aim:

Cholangiocarcinoma typically presents as

biliary strictures; an accurate diagnosis is fundamental to address

the best management. Although intraductal brushing during ERCP

is the designated method for tissue sampling of biliary strictures, its

sensitivity is low varying between of 27% to 56%. Spyglass system also

known as Peroral cholangioscopy (POC) permits direct visualization

and biopsies of the biliary tree for diagnostic procedures. The aim of

this video case was to show the usefulness of the next generation of

Spyglass system for the characterization of a indeterminate biliary

stricture.

Material and methods:

A 70 years old male with a suspected

lesion located in the head of the pancreas, identified at CT scan and

associated with a biliary stricture underwent EUS and ERCP. At that

time brush cytology and fine needle aspiration (FNA) were performed

and a plastic biliary stent was successfully placed. Despite the

improvement of the patient symptoms, a certain diagnosis was not

made due to inconclusive results of brush cytology and FNA. After

a few months, following the worsening of the patient conditions, a

next generation of Spyglass system was performed during the ERCP

in order to charachterise the indeterminate biliary stricture.

Results:

During the ERCP a clogged plastic biliary stent (Olympus

double layer, 6cm 10 Fr) was identified in placed and removed using

a polypectomy snare. Once the cholangiography was performed, a

stricture located in the distal common bile duct was identified and

dilated using a 12mm balloon dilatation. A SpyGlass assessment of

the biliary tract was then successfully performed and an endophyting

irregular and ulcerated lesion was located in the distal common

bile duct. Multiple targeted biopsies were then taken through the

spyglass biopsies channel using a dedicated biopsies forceps. A 6

cm uncovered metallic stent was then placed. The histopathological

analysis confirmed a pancreatic neoplasia involving the biliary duct.

Conclusions:

The next generation SpyGlass system appeared to be

an useful and safe technique that allows the characterization of an

indeterminate biliary stricture and it can be easily performed by

one operator. In addition, the improvement of the images quality,

compare to the previous generation of SpyGlass system, allows an

accurate inspection of the biliary tract.

V.02.10

AN INNOVATIVE EVALUATION OF PANCREATIC CYSTS BY

CONFOCAL LASER ENDOMICROSCOPY AND FIBER OPTIC

LIGHTING DIRECT VISUALIZATION SYSTEM

Gaia S.*, Bruno M., Ribaldone D.G., Fasulo R., Marietti M.,

De Angelis C.

AUO Città della Salute e della Scienza, Gastroenterology and

Endoscopy Unit, University of Turin, Turin, Italy

Background and aim:

Pancreatic cysts are a frequent diagnostic

challenge. Endoscopic ultrasound (EUS) with Fine Needle Aspiration

is often used for differential diagnosis, but both cytology and cystic

fluid analysis are often inconclusive.

Material and methods:

We report a video showing the exploration

of two different pancreatic cysts with both confocal laser

endomicroscopy (CLE) probeby Cellvizio (AQ flex probe; Mauna Kea

Technologies) and direct visualization by SpyGlass System (Boston

Scientific).

Case A: a 75-year-old woman presented with an incidentally

discovered, 4 cm cyst of the pancreatic body identified on CT scan.

Case B: a 45-year-old woman presented with a slightly growing 6

cm cyst of the pancreatic tail and two previous episodes of acute

pancreatitis. On EUS exploration contrast enhanced thin peripheral

septa were detected.

The cysts were punctured with a 19 gauge Expect Flexible Needle

(Boston Scientific) in which the CLE probe and SpyGlass optic fiber

were introduced.

Results:

Macroscopic and microscopic images of the pancreatic

wall are provided in the VIDEO and the utility of CLE and Spyglass

is discussed comparing the diagnostic yield of these innovative

procedures with cyst cytology and CEA/amylase levels in the cystic

fluid.

Conclusions:

New promising devices are available to obtain a

definite diagnosis of pancreatic cysts by direct endoscopic and

microscopic exploration.

V.02.11

EUS GUIDED CISTO-GASTRIC DRAINAGE AFTER EUS-GUIDED

GASTRO-GASTRIC ANASTOMOSIS TO TREAT A SIMPTOMATIC

PANCREATIC PSEUDOCYST IN PATIENT WITH ROUX–EN-Y

GASTRIC BY-PASS: THE DREAM BECAMES REALITY!

Sica M.*, Manta R., Tringali A., Mutignani M.

Surgical Digestive Diagnostic and Interventional Endoscopy, “Niguarda

Ca’ Granda Hospital”, Milano, Italy

Background and aim:

From 10% to 15% of acute pancreatitis is

complicated by pancreatic pseudocysts, which show spontaneous

resolution in 50% of the cases. Treatment is indicated in symptomatic

or complicated persistent pseudocysts. Drainage of pancreatic

pseudocysts using endoscopic techniques is the current preferred

method.